Port Adelaide defender Esava Ratugolea will be assessed this week ahead of Round 1.
Ratugolea underwent a knee arthroscopy last month and has now integrated back into full training.
Small forward Tom Anastasopoulos will have ankle surgery to repair a syndesmosis injury.
The 19-year-old went down during the club’s internal trial match on Friday, with scans over the weekend revealing the extent of the injury.
Vice-captain Zak Butters, key defender Brandon Zerk-Thatcher and forward Todd Marshall are all progressing well in their recovery.
Port Adelaide will name its team for Saturday’s Round 1 game against Collingwood on Thursday at 5:50pm ACDT.
Injury list
Esava Ratugolea (knee) - test
Zak Butters (knee) - 4-6 weeks
Tom Anastasopoulos (ankle) - 4-6 weeks
Brandon Zerk-Thatcher (back) - 7-9 weeks
Todd Marshall (achilles) - TBC
Injury report: Ratugolea to be assessed
The defender underwent a knee arthroscopy last month and has now integrated back into full training.