Enemy Lines: Key opposition players to miss Rounds 22, 23.
Several Blues touch-and-go, Fyfe banned for two games and Barlow out for two weeks.
His teammate, key midfielder Michael Barlow, is also set to miss the Power's Round 23 match against the 'purple haze'.
The news comes as Port Adelaide's immediate opponent, Carlton, is likely to lose several crucial players through injury on Friday night.
Friday night blockbuster nearly sold out
Brock McLean (calf) and David Ellard (ankle) have both been ruled out of the Blues line-up for Friday night, and Dale Thomas (knee) and Tro Menzel (shoulder) are in doubt to play.
carltonfc.com.au reports Andrew McInnes, Kane Lucas, Patrick Cripps and Matthew Watson, as well as ruckman Matthew Kreuzer will be considered to come into the side.
Fremantle's Barlow has been listed as a two-week return prospect from a thumb injury, meaning he would likely be in line to play his first game post-rehab in the opening week of finals.
Michael Walters is likely to play against Brisbane this week despite pulling up sore from Sunday's victory over the Hawks.
At Alberton, Port Adelaide is poised to enter Round 22 with its healthiest list since the start of the year, with all three of Jackson Trengove, Angus Monfries and Hamish Hartlett expected to play the Blues.
Port Adelaide injury update
Campbell Heath is also a chance to return from LARS surgery on his knee via the SANFL against Glenelg on Saturday.
Port Adelaide plays Carlton at 7:20pm on Friday at the Adelaide Oval and Glenelg in the state leagueat Glenelg Oval at 2:10pm on Saturday.