He's the only change to the Power's team so, with Kane Mitchell the only as-yet confirmed omission.
The club's leading SANFL goal kicker John Butcher and in-form Magpie midfielders Paul Stewart and Ben Newton have been included on the extended bench.
Port Adelaide is hunting for a win after three consecutive losses.
It will also be Cassisi's final ever AFL game after he confirmed his retirement on Thursday.
The Power will confirm a final 22 at 4:30pm on Friday.
Sunday 20 July, 12:40pm, Adelaide Oval
FB: Cam O’Shea, Jack Hombsch, Dom Cassisi
HB: Matthew Broadbent, Tom Jonas, Jasper Pittard
C: Jared Polec, Travis Boak, Kane Cornes
HF: Paul Stewart, Justin Westhoff, Matt White
FF: Robbie Gray, Jay Schulz, Chad Wingard
Foll: Matthew Lobbe, Ollie Wines, Brad Ebert
Interchange from: Hamish Hartlett, John Butcher, Jarman Impey, Ben Newton, Aaron Young, Tom Logan, Sam Gray
In: Butcher, Cassisi, Newton, Stewart
Out: Mitchell (omitted)
Milestones: Cassisi, final AFL game (retiring)
